{"id":60670,"date":"2018-08-06T21:38:27","date_gmt":"2018-08-07T01:38:27","guid":{"rendered":"http:\/\/johncohn.org\/base\/?p=60670"},"modified":"2018-08-06T21:38:27","modified_gmt":"2018-08-07T01:38:27","slug":"monday-night-technetium","status":"publish","type":"post","link":"http:\/\/johncohn.org\/base\/2018\/08\/06\/monday-night-technetium\/","title":{"rendered":"Monday night &#8211;  Technetium"},"content":{"rendered":"<p>I am radioactive !&#8230;&nbsp;<\/p>\n<p>At least for the next couple of hours .<\/p>\n<p>&nbsp;<\/p>\n<p>I had a cardiac stress test today.. as I do about every 5 years.; it&#8217;s something my doc has me do bcause of the family history we have.. it&#8217;s &nbsp;kinda &nbsp;fun.. you get on a treadmill then they shoot you up with a radioactive gamma-emitting isotope (<sup>99<\/sup>Tc).. then they put you in a gamma CT scanner.. Every time it tells me I&#8217;m fine.. and today was the same. &nbsp;<\/p>\n<p>It does get me thinkign of the wierd life of Isotopes.. .. I read about&nbsp;<sup>99<\/sup>Tc &nbsp;.&nbsp;<\/p>\n<p>It &nbsp;was discovered in 1938 by&nbsp;<a title=\"Emilio Segr\u00e8\" href=\"https:\/\/en.wikipedia.org\/wiki\/Emilio_Segr%C3%A8\">Emilio Segr\u00e8<\/a> and <a title=\"Glenn T. Seaborg\" href=\"https:\/\/en.wikipedia.org\/wiki\/Glenn_T._Seaborg\">Glenn T. Seaborg<\/a> after bombarding natural molybdenum with 8 MeV <a class=\"mw-redirect\" title=\"Deuteron\" href=\"https:\/\/en.wikipedia.org\/wiki\/Deuteron\">deuterons<\/a> in the 37-inch (940&nbsp;mm) <a title=\"Cyclotron\" href=\"https:\/\/en.wikipedia.org\/wiki\/Cyclotron\">cyclotron<\/a> of <a class=\"mw-redirect\" title=\"Ernest Orlando Lawrence\" href=\"https:\/\/en.wikipedia.org\/wiki\/Ernest_Orlando_Lawrence\">Ernest Orlando Lawrence<\/a>&#8216;s <a title=\"Lawrence Berkeley National Laboratory\" href=\"https:\/\/en.wikipedia.org\/wiki\/Lawrence_Berkeley_National_Laboratory\">Radiation laboratory<\/a>.<sup id=\"cite_ref-2\" class=\"reference\"><a href=\"https:\/\/en.wikipedia.org\/wiki\/Technetium-99m#cite_note-2\">[2]<\/a><\/sup><sup id=\"cite_ref-3\" class=\"reference\"><\/sup><\/p>\n<p>I learned that the doeses.. which &nbsp;are only useful fro about 6 hours are made locally by a company in Willisont using soemthing called a &#8216;Moly Cow&#8221; .. .. which Wikipedia helpfully explains thus:<\/p>\n<p><img decoding=\"async\" class=\"aligncenter\" title=\"\" src=\"http:\/\/johncohn.org\/base\/wp-content\/uploads\/2018\/08\/tc.png\" alt=\"\"><\/p>\n<blockquote><p>Technetium-99m&#8217;s short half-life of 6 hours makes storage impossible and would make transport very expensive. It is instead its parent nuclide <sup>99<\/sup>Mo that is supplied to hospitals after its extraction from the neutron-irradiated uranium targets and its purification in dedicated processing facilities.<sup id=\"cite_ref-56\" class=\"reference\"><a href=\"https:\/\/en.wikipedia.org\/wiki\/Technetium-99m#cite_note-56\">[notes 1]<\/a><\/sup><sup id=\"cite_ref-Dilw_57-0\" class=\"reference\"><a href=\"https:\/\/en.wikipedia.org\/wiki\/Technetium-99m#cite_note-Dilw-57\">[56]<\/a><\/sup> It is shipped by specialised radiopharmaceutical companies in the form of <a title=\"Technetium-99m generator\" href=\"https:\/\/en.wikipedia.org\/wiki\/Technetium-99m_generator\">technetium-99m generators<\/a> worldwide or directly distributed to the local market. The generators, colloquially known as a moly cows, are devices designed to provide radiation shielding for transport and to minimize the extraction work done at the medical facility. A typical dose rate at 1 metre from Tc-99m generator is 20-50 <a class=\"mw-redirect\" title=\"\u039cSv\/h\" href=\"https:\/\/en.wikipedia.org\/wiki\/%CE%9CSv\/h\">\u03bcSv\/h<\/a> during transport.<sup id=\"cite_ref-58\" class=\"reference\"><a href=\"https:\/\/en.wikipedia.org\/wiki\/Technetium-99m#cite_note-58\">[57]<\/a><\/sup> These generators&#8217; output declines with time and must be replaced weekly, since the half-life of <sup>99<\/sup>Mo is still only 66 hours.<\/p>\n<p>Molybdenum-99 spontaneously decays to excited states of <sup>99<\/sup>Tc through <a title=\"Beta decay\" href=\"https:\/\/en.wikipedia.org\/wiki\/Beta_decay\">beta decay<\/a>. Over 87% of the decays lead to the 142 keV excited state of Tc-99m. A<br \/>\n\u03b2<sup>\u2212<\/sup><a title=\"Electron\" href=\"https:\/\/en.wikipedia.org\/wiki\/Electron\">electron<\/a>and a \u03bd<sub>e<\/sub><a class=\"mw-redirect\" title=\"Electron antineutrino\" href=\"https:\/\/en.wikipedia.org\/wiki\/Electron_antineutrino\">electron antineutrino<\/a> are emitted in the process (<sup>99<\/sup>Mo \u2192 <sup>99m<\/sup>Tc + \u03b2<sup>\u2212<\/sup>+ \u03bd<sub>e<\/sub>). The \u03b2<sup>\u2212<\/sup><br \/>\nelectrons are easily <a class=\"mw-redirect\" title=\"Radiation shielding\" href=\"https:\/\/en.wikipedia.org\/wiki\/Radiation_shielding\">shielded<\/a> for transport, and <sup>99m<\/sup>Tc generators are only minor radiation hazards, mostly due to secondary X-rays produced by the electrons (also known as <i><a title=\"Bremsstrahlung\" href=\"https:\/\/en.wikipedia.org\/wiki\/Bremsstrahlung\">Bremsstrahlung<\/a><\/i>).<\/p>\n<p>At the hospital, the <sup>99m<\/sup>Tc that forms through <sup>99<\/sup>Mo decay is chemically extracted from the technetium-99m generator. Most commercial <sup>99<\/sup>Mo\/<sup>99m<\/sup>Tc generators use <a title=\"Column chromatography\" href=\"https:\/\/en.wikipedia.org\/wiki\/Column_chromatography\">column chromatography<\/a>, in which <sup>99<\/sup>Mo in the form of water-soluble molybdate, MoO<sub>4<\/sub><sup>2\u2212<\/sup> is <a title=\"Adsorption\" href=\"https:\/\/en.wikipedia.org\/wiki\/Adsorption\">adsorbed<\/a> onto acid alumina (Al<sub>2<\/sub>O<sub>3<\/sub>). When the <sup>99<\/sup>Mo decays, it forms <a title=\"Pertechnetate\" href=\"https:\/\/en.wikipedia.org\/wiki\/Pertechnetate\">pertechnetate<\/a> TcO<sub>4<\/sub><sup>\u2212<\/sup>, which, because of its single charge, is less tightly bound to the alumina. Pulling normal saline solution through the column of immobilized <sup>99<\/sup>MoO<sub>4<\/sub><sup>2\u2212<\/sup><a class=\"mw-redirect\" title=\"Elute\" href=\"https:\/\/en.wikipedia.org\/wiki\/Elute\">elutes<\/a> the soluble <sup>99m<\/sup>TcO<sub>4<\/sub><sup>\u2212<\/sup>, resulting in a saline solution containing the <sup>99m<\/sup>Tc as the dissolved <a title=\"Sodium pertechnetate\" href=\"https:\/\/en.wikipedia.org\/wiki\/Sodium_pertechnetate\">sodium salt of the pertechnetate<\/a>. One technetium-99m generator, holding only a few micrograms of <sup>99<\/sup>Mo, can potentially diagnose 10,000 patients<sup class=\"noprint Inline-Template Template-Fact\">[<i><a title=\"Wikipedia:Citation needed\" href=\"https:\/\/en.wikipedia.org\/wiki\/Wikipedia:Citation_needed\"><span title=\"This claim needs references to reliable sources. (May 2012)\">citation needed<\/span><\/a><\/i>]<\/sup> because it will be producing <sup>99m<\/sup>Tc strongly for over a week.<\/p><\/blockquote>\n<p>Well.. that makes me feel better<\/p>\n<p>The only let down.. is that I don&#8217;t appear to have gained any super powers<\/p>\n<p>shucks<\/p>\n<p>nite all, nite sam<\/p>\n<p>-me<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I am radioactive !&#8230;&nbsp; At least for the next couple of hours . &nbsp; I had a cardiac stress test today.. as I do about every 5 years.; it&#8217;s something my doc has me do bcause of the family history we have.. it&#8217;s &nbsp;kinda &nbsp;fun.. you get on a treadmill then they shoot you up &hellip; <a href=\"http:\/\/johncohn.org\/base\/2018\/08\/06\/monday-night-technetium\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Monday night &#8211;  Technetium<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-60670","post","type-post","status-publish","format-standard","hentry"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/posts\/60670","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/comments?post=60670"}],"version-history":[{"count":1,"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/posts\/60670\/revisions"}],"predecessor-version":[{"id":60672,"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/posts\/60670\/revisions\/60672"}],"wp:attachment":[{"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/media?parent=60670"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/categories?post=60670"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/johncohn.org\/base\/wp-json\/wp\/v2\/tags?post=60670"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}